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pentobarbital decreases levels of ponatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Steer clear of Except if the coadministration outweighs the feasible risk of ponatinib underexposure; watch for signs of reduced efficacy.pentobarbital will lessen the extent or outcome of terbinafine by infl